Biomarker for Diagnosis of Chronic Kidney Disease
2311 - “Lead Inventors: Jonathan Matthew Barasch, M.D., Ph.D., Nicholas Barasch Chronic Kidney Disease and Acute Kidney Disease Pose Diagnostic Difficulty: Establishing whether a patient has chronic...
View ArticleMouse for human mitochondrial respiratory chain disease
2651 - “Lead Inventor: Eric A. Schon Ph.D. Mitochondrial respiratory chain disease studies using mouse model : Mitochondrial respiratory chain disease is a heterogeneous disorder, and several genes...
View ArticleHemodialysis Access Flow Restrictor Device for End-Stage Renal Disease (ESRD)
2732 - “Lead Inventor: Judah Weinberger, MD, PhD Hemodialysis for End-Stage Renal Disease (ESRD) Increase Cardiac Risks with Increased Blood Flow In the US, about 400,000 patients require chronic...
View ArticleTransgenic Mouse Strain for Visualization of Epithelial Cells during Renal...
2986 - “Lead Inventor: Franklin D. Costantini, Ph.D. Transgenic Visualization Techniques for Individual Cell Study in Renal Morphogenesis Although many of the genes involved in renal branching...
View ArticleA transgenic Ngal reporter mouse detects kidney injury in real time
2172 - The Ngal reporter mouse allows for rapid real time assaying of kidney damage by linking expression of neutrophil gelatinase-associated lipocalin with a bioluminescent/fluorescent read-out. The...
View ArticleTransgenic mouse strain allows inducible genetic expression in kidney cells...
cu14313 - Mouse models play an important role in the study of diseases. The Cre-LoxP recombination system has become a useful tool in controlling genetic expression in transgenic mice and permits the...
View ArticleClinically proven fluorenone compound for the treatment of gout
cu15291 - Gout is estimated to affect 1-2% of the population of the Western world, with 8 million sufferers in the US alone. This inflammatory disease is caused by a buildup of uric acid in the...
View Article
